Plot
Seth Brundle (Jeff Goldblum), a brilliant but eccentric scientist, meets Veronica Quaife (Geena Davis), a journalist for Particle magazine, at a meet-the-press event held by Bartok Science Industries, the company that provides funding for Brundle's work. Seth shows Veronica a project that will change the world: a set of "Telepods" that allows instantaneous teleportation of an object from one pod to another. Veronica is impressed and eventually agrees to document Seth's work. Although the telepods can transport inanimate objects perfectly, they do not work correctly on living things. Seth and Veronica begin a romantic relationship, and their first sexual encounter provides inspiration for Seth, who sets about successfully reprogramming the telepod computer to cope with living flesh.Seth then succeeds in teleporting a second baboon with no apparent harm. Flush with this success, Brundle want to spend a romantic evening with Veronica, but she suddenly departs before they can celebrate. Brundle's judgment soon becomes impaired by alcohol and his paranoid fear that Veronica is secretly rekindling her relationship with her editor and former lover, Stathis Borans (John Getz). A drunk and jealous Brundle decides to teleport himself, but a common housefly slips into the pod, unseen. The teleportation successful, Brundle emerges from the receiving pod, seemingly normal. Shortly after his teleportation, Seth begins to exhibit what at first appear to be beneficial effects of the process—such as increased strength, stamina and sexual potency. However, he soon becomes arrogant and violent, and eventually realizes that something went horribly wrong when his fingernails begin falling off. Brundle checks his computer's records, and discovers that the telepod computer, confused by the presence of two separate life-forms in the sending pod, merged him with the fly at the molecular-genetic level.